Physicians are becoming more entrepreneurial in response to threats to their practices and the sick-care innovation imperative. Some, particularly those without a medical background or who have never practiced medicine, ask whether doctors should be doctors or entrepreneurs and press them to commit to being “all in” if they are to be successful as a physician entrepreneur. We need to stop thinking “either/or.” Many physicians think they can be both and, in fact, that adopting an entrepreneurial mindset helps them be better doctors. I agree.